On April 17, 2026, Professor Kazuhiko Ishihara, a world-renowned expert in the field of biomaterials, recipient of the Japanese Order of the Sacred Treasure, Gold Rays with Purple Ribbon, and Emeritus Professor of the University of Tokyo, led a delegation to visit the R&D Center of PTG Passion Technology Group. The core purpose of this visit was to share his decades of cutting-edge R&D and industrialization experience in the field of biomimetic cell membrane technology. The PTG R&D team listened attentively and actively consulted throughout the process, conducting in-depth exchanges regarding the application of the technology across China, Spain, Japan and Egypt, which injected core momentum into the company's subsequent technological upgrading and helped promote the R&D and implementation of biomimetic cell membrane technology in related fields.
Professor Ishihara is the founder of the MPC series of polymers for biomimetic cell membrane materials. He has been deeply engaged in the R&D and industrialization of this technology for decades, achieving the world's first kilogram-scale synthesis of "MPC polymer materials", laying a core theoretical foundation and establishing a complete system of "biomimetic phospholipid biointerface materials", which has powerfully promoted the large-scale application of the technology in the field of local targeted delivery. He has presided over many key national scientific research projects in Japan, published more than 800 academic papers with a total of over 20,000 citations and an H-index of 79. Originating from top-tier scientific research, this biomimetic cell membrane technology serves not only as a "meritorious material" supporting life and health in the medical field, but also as a transformative, game-changing core technology that delivers a dimension-reducing impact to the skincare industry.
During this visit, Professor Ishihara shared his core technological achievements and industrialization experience refined through three generations of iteration over more than 30 years. As early as 1995, the first generation of this technology was first adopted by POLA, a high-end Japanese skincare brand, for its flagship premium restorative cream. Priced at 30,000 yen for a 30g unit, it sold 200,000 bottles in the first month of its launch, with sales exceeding 6 billion yen. A recipient of Japan's prestigious Medal with Purple Ribbon, this cutting-edge biomaterial technology has solved three major core challenges in the industry by virtue of its exceptional biocompatibility, superior moisture-inducing properties and outstanding anti-adhesion capabilities. Prior to this, it has been widely applied in medical fields such as artificial hearts, artificial kidneys and drug delivery systems, and has significantly extended the service life of artificial hip joints. Meanwhile, relying on its excellent skin affinity and moisture-locking performance, it is also applied in high-end contact lenses and skincare products, appearing in cosmetic formulations as Polyquaternium-51 (MPC). PTG will also take this opportunity to continue promoting the translation and commercialization of this rare and precious medical-grade biomimetic cell membrane technology in the daily chemical field, achieve product innovation and upgrading with world-class cutting-edge science and technology, and bring dimension-reducing empowerment of medical-grade ingredients to the industry.
Dr. Li Ziyin, who accompanied the delegation, is a core R&D expert of PTG. He has long been engaged in the field of polymer biomaterials, with a solid academic background of dual doctoral degrees from the University of Tokyo and Tsinghua University. He has won honors such as the Japanese MEXT Scholarship and JSMS "Outstanding Young Scientist" award, and holds 8 invention patents and having profound technical accumulation in the R&D and application of biomimetic materials. Dr. Gao Botao is a research expert at the Institute of Biology and Medical Engineering, Guangdong Academy of Sciences, focusing on regenerative medicine materials research with rich academic and scientific research experience. He accompanied the delegation to assist in sharing technologies, helping the PTG team understand the core technical points more accurately.
During the exchange, combining decades of R&D practice, Professor Ishihara systematically shared the core advantages of biomimetic cell membrane technology in biocompatibility and active molecule delivery efficiency around its multi-scenario applications, and focused on interpreting technical characteristics such as neutral charge design and high biocompatibility. Taking his own skin condition as a case, combined with the real experience of "using" relevant skincare products in long-term experiments, he intuitively demonstrated the obvious effects of this technology in moisturizing and barrier repair, and deeply explained the core principle: by simulating the structure of human cell membranes, it effectively avoids charge repulsion, reduces component agglomeration, greatly improves the transdermal absorption rate of active molecules, and solves the pain points of traditional delivery technologies such as difficulty in water-soluble components penetrating the stratum corneum and easy leakage and inactivation of carriers. Every technical detail was explained in detail with substantial content. The PTG team listened to Professor Ishihara's sharing throughout the process, and discussed key issues such as the difficulties in the application of biomimetic cell membrane technology in skincare, hair care, body management and other fields, as well as the direction of technical optimization with Professor Ishihara one by one. The core value of biomimetic cell membrane technology lies in "safety, efficiency and multi-adaptability", and Professor Ishihara encouraged the PTG team to deepen their research on the technology and promote its innovative application in related fields.
Professor Kazuhiko Ishihara's visit this time is an important opportunity for PTG Passion Technology to absorb cutting-edge technical experience and clarify the application direction. It not only enabled the PTG team to gain cutting-edge knowledge and practical experience in the field of biomimetic cell membrane technology, but also clarified the core direction of technology implementation. At the end of the exchange, PTG invited Professor Ishihara to visit the upcoming Tokyo business office, which the professor readily agreed to, and expressed high optimism about the company's future technological R&D and development prospects. In the future, PTG will continue to focus on the implementation of biomimetic cell membrane technology, focus on the daily chemical fields, build highly competitive products with cutting-edge biotechnology, promote the in-depth integration of technology and industry, deepen the innovative application of biomimetic cell membrane technology in new daily chemical products, and transform cutting-edge scientific research achievements into premium skincare and personal care products benefiting more consumers.
